Infertility Fertility Center
Infertility Fertility Center of Women was established in 1372 and one of the first acts for the treatment of infertility Infertility fertility centers in Iran. In the center of infertility methods such as intrauterine insemination (IUI) Sex selection Sex selection And in vitro fertilization and embryo transfer into the uterus (IVF) Direct injection of sperm into the egg and transfer to the uterus (ICSI)Transfer of embryos into the fallopian tube. (ZIFT) These acts are performed using conventional infertility
The center’s services include:
The new method of isolating spermatozoa
This method is suitable for patients with the following conditions:
1. Patients who have poor sperm parameters.
2. Two unsuccessful ICSI.
3. Hurt sperm genome (TUNEL above).
Preparation methods sperm into an egg to sperm injection, in the success of Heydemann Policy, especially micro method (Intra-cytoplasmic sperm injectionICSI:) Plays a very important role. In common Tytknyk Micro, sperm motility and morphology of spermatozoa is usually based on two indicators, but studies have shown that with these two indicators alone can not be the best Asprmra selected. Thus, recent studies on new separation methods based on molecular and functional characteristics of sperm have begun to focus, not only the best sperm morphology and motility but also in terms of performance and safety of their choice. One of these separation methods, methods of sperm selection in the magnetic field (MACS: Magnetic-activated cell sorting system) That Salmbh used to separate sperm.Unhealthy sperm markers on their surface, and studies have shown that Annexin material attached to the iron molecule’s ability to bind to the marker. In this method, annexin mixed with sperm and then placed in a magnetic field. So unhealthy sperm binds to iron in the magnetic field due hang annexin remain. If the sperm are healthy and fit through it. So with this separation can be additionally healthy sperm selection based on the movement and shape of the sperm was isolated.
Intra-uterine insemination (IUI)
IUI is one of the easiest and cheapest ways to treat infertility in which sperm is artificially injected into the uterus with a thin tube for. In this way, the chances of sperm reaching the egg and its subsequent increasesthe chances of fertilization and pregnancy. .
◄ IUI in what is useful?
1. In cases where the test PCT ( Test after marriage) is abnormal .
2. In cases where the number, mobility and shape of sperm is not appropriate .
In case of paragraph 2 is too abnormal, do ICSI it is suggested .
3. In cases where the cause of infertility, anti-sperm antibodies in semen. in this case
with the method IUI , Sperm healthy and undamaged, isolated and injected into the uterus .
4. Ejaculation problems in men who have .
5. For couples who are having difficulty in relationships and sperm into the vagina will not be .
6. In cases of mild endometriosis
◄ preparation before IUI
• IUI can be done with or without the use of drugs that stimulate ovulation. But since the use of fertility drugs increase the number of mature oocytes is therefore increase the chances of fertility. Usually, these drugs are in the process IUI Used .
• Couples need about a week before menstruation to preliminary investigations, such as vaginal examination, sperm, ultrasound visit .
• After an ultrasound examination of the uterus and Tkhmda them, ovulation induction drugs for patients on the third day of the menstrual given .
• The patient again about the twelfth to eleventh day of menstruation ultrasound and ultrasound again depending on the size of eggs perched on prescribed medication for patients .
• Consecutive patients with sonography can be controlled to the extent that the size of the egg perched about 16 to 20 mm reach .
• Then the patient mates HCG Given .
• The most suitable time to perform IUI Approximately 34 to 36 hours after injection HCG is .
• Morning IUI Semen sick wife in sterile containers and delivered to the lab after washing, sperm quality is isolated. Sperm preparation process takes about 60 to 120 minutes .
• Then the patient is placed on the examination table, the doctor uses a special catheter were washed sperm into the uterus through the cervix and injecting the guide .
◄ chance of success IUI
Chances of success IUI About 10 to 20 percent. .
– The potential risks of surgery IUI
Rarely, infection, pain in the heart, like pain during menstruation, twining and Hayprastymvlyshn syndrome (overstimulation of their Tkhmda )
– Essential Facts
1. Surgery IUI Will not hurt .
2. Surgery IUI Do not require anesthesia except in rare cases the patient does not cooperate or patient inability to have intercourse (vaginismus ).
3. After doing IUI There is usually bleeding but if you use forceps to achieve the cervix may arise from the forceps little bleeding. In addition, some women during ovulation slight bleeding that require no special action is not .
4. Performed immediately after sexual intercourse IUI Increases the chances of pregnancy, but is recommended if you have bleeding couples not married to 48 hours .
5. The use of painkillers like Aypvprvfn, mefenamic acid and after IUI Not recommended for uterine pain .
6. After surgery IUI No need to lie down because the cervix does not open holes remain, but some doctors recommend 15 to 20 minutes of rest .
7. If you have uterine pain after discharge can rest at home, but otherwise the rest is not needed but lifting heavy objects and doing heavy physical activities until the situation Avoid Pregnancy .
8. Do common tasks and swimming, 48 hours after IUI Is accepted .
9. Possible after IUI Feel that you are out of sperm, sperm into the uterus if he directed loosen the mucus of the cervix may be discharged out this created the impression you have left sperm .
10. Having about 3 to 4 mature follicles, the greatest chance of success in IUI Is. Having more without increasing the number of follicles will be successfully increases the chances of multiple birth .
11. 14 to 17 days after IUI In the absence of menstruation, pregnancy blood test to do, if it is negative. A month later, the first day of menstruation to see your doctor and be positive if the test two weeks after undergoing an ultrasound to see your doctor .
12. If after doing IUI The doctor’s supervision treated with progesterone (progestin) as injections, suppository, or tablet you’re waiting periods on their own. 17 days after IUI Pregnancy blood test done and the results to your doctor. (In case of negative drug test cut must be achieved to menstruation ).
13. On the day IUI Sperm samples according to doctor’s written order, call . Use soap, gel, etc. due to bacteriostatic properties of sperm, is not recommended .
14. If sperm samples are taken from home or hotel to the center location should not be more than 30 minutes. .
In vitro fertilization (IVF)
At the time of the birth of the first baby of treatment IVF In 1978, the treatment brought new hope for infertile couples . IVF Fertility treatment is a method in which a woman’s egg and a man’s sperm outside the body in the container, put together in vitro fertilization with each other to find after fertilization, the embryos obtained a three-day two narrow tubes, for into the uterus she transferred .
◄ What to do IVF Elected?
1. High 2. Women aged women with blocked or damaged fallopian tubes (3) women with a history tubal ligation (tubal ligation) and called for the fertility of women with endometriosis re 4. 5. 6. couples withunexplained infertility patients IUI 7. multiple unsuccessful sperm abnormalities Moffitt action Shvhrmyzan IVF Depends on several factors, including age, status egg and sperm used in the process of ovulation,accuracy embryology laboratory specializing in women .
IVF success rate is estimated at about 35 percent.
◄ steps IVF:
– Step ovulation :
Fertility drugs to get high egg and the formation of several fetuses and increase the chances of fertility prescribed. They’re usually on the second day of menstruation and after ultrasound and ensure the integrity of the uterus and ovaries administration severely lead. Growth eggs with ultrasound successive patient follow-up. Therefore, it is possible to reach the ideal situation several times at intervals of 2 to 3 days to be placed under ultrasound, the ultrasound follicle size of 18 to 20 mm, mates HCG The final oocyte maturation prescribed. Time injections HCG It is very important because approximately 34 to 36 hours after injection ovulation and therefore time should be determined according to the doctor to release eggs to be collected .
– Collect the egg and sperm :
Be sure the patient is fasting on the day of oocyte. Semen from the patient’s wife prepared and delivered to the laboratory. After washing and preparation of laboratory samples to the laboratory it IVF Delivers. A mild anesthetic to the patient in the operating room during the process of egg Kgyry any discomfort. Then the eggs perched under direct vision with Ultrasonic devices made by a very thin needle and tube forcollection and laboratory IVF Delivered .
– In vitro fertilization fetus was submerged :
in the lab IVF Egg perched in follicular fluid is separated, washed and placed in a medium inside the container. Wife washed sperm lab which had already been delivered along with this egg is placed in the container, the container samples of sperm and eggs in incubator CO2 Placed at 37 ° C to spontaneously find each other fertilization. The next morning when the fertilized embryos into the incubator for 24 to 48 hours are 4 to 8-cell stage to reach .
– Transfer or embryo transfer into the uterus :
Usually three days after oocyte embryos transferred to the uterus (blastocyst embryos if they will be transferred five days later). Usually about 2 to 4 embryo transfer into the uterus during data transmission, and the remaining embryos if appropriate using the stored embryos are stored by freezing in the event of failure of the next treatment cycle used. Embryo transfer is done in the operating room but do not require anesthesia.Only patients were examined on the bed and then embryos thin tube through the hole for the mouth of the uterus, is sent to the uterus. This process is painless but sometimes mild pain feels .
After transfer and short breaks, guiding the patient to the hospital and a few hours after the clearance .
– Complications IVF:
Hayprastymvlyshn syndrome (overstimulation of the ovaries), rarely anesthesia, bleeding, infection, damage to the Rv BC, bowels and bladder during oocyte and twining
In case of problems following immediately contact your doctor or medical staff :
Spotting 1. 2. 3. Shortness of breath, abdominal pain, fever over 38 ° C 4. 5. Blood in the urine
ICSI (ICSI)
Microinjection technique (injection of sperm into the egg cytoplasm) in the treatment of major transformation created with male factor infertility. This technique for the first time in Belgium in 1992 was used for the treatment of male infertility and its success stems from the expansion of secondary and minor creature using this method, this method uses a microscope with high magnification embryologists are able to differentiate normal from abnormal is in conflict spray after immobilizing the sperm is injected into an egg by a needle so thin it out .
Microinjection action in 30 to 40 percent of cases the cause is performed with male factor infertility .
◄ ICSI fertility chance in the following increases :
Spray a small number of skills, poor motility of sperm, sperm with abnormal forms large tract blockage that prevents the free sperm is sperm, sperm antibodies, in the case of vasectomy, in case of fertilization or poor fertilization IVF And in the case of sperm in the testis biopsies
◄ steps ICSI
– Step ovulation :
Fertility drugs to get high egg and the formation of several fetuses and increase the chances of fertility are given. They’re usually on the second day of menstruation and after ultrasound and ensure the integrity of the uterus and ovaries administration severely lead. Egg perched growth sequentially followed with sonography teeth, so may the patient to reach the ideal situation several times at intervals of 2 to 3 days to be placed under ultrasound, the ultrasound follicle size of 18 to 20 mm, mates HCG The final oocyte maturation is prescribed. Time injections HCG It is very important because approximately 34 to 36 hours after injection ovulation and therefore time should be determined according to the doctor to release eggs to be collected .
– Gathers eggs :
Be sure the patient is fasting on the day of oocyte. The patient is placed in the operating room under a mild anesthetic to relieve any discomfort during the process of oocyte. Oocytes, with a direct view ultrasound, dragged by a very thin needle and tube were collected for laboratory IVF Delivered. The collected eggs are covered by a set of granulosa cells, these cells Kanzym the problem with low pipetting and passing a row of thin glass is removed. Free eggs from these cells under a microscope and the complete separation of granulosa cells and oocyte maturation, allowing it through ICSI Intracytoplasmic Sperm Injection prepares .
– Collect sperm :
If the wife is ill on the day of oocyte capable of collecting semen, fresh semen wife washed and prepared in the laboratory to laboratory. IVF The microinjection delivery. Sometimes the sperm microinjection technique PESA Or FNA ( Using a syringe of testicular local Yhsy b) or with TESE Or testicular biopsy (a sample directly from the testes under general anesthesia) is prepared, carry out the procedure by Urologists and when it is determined by the urologist and if done before the day of oocyte, sperm frozen and on the day of oocyte freezing out .
– Fertilization and embryo development :
in the lab IVF , Embryologists using a microscope with high magnification injects sperm into an egg with a needle thin. Days after the injection, egg perched fertility evaluated and, if the fertilized egg, 48 hours are also put into the incubator to reach 8-cell embryo .
– Transfer or embryo transfer into the uterus :
Usually embryos transferred to the uterus three days after oocyte It is a (if not the blastocyst embryo transfer will be five days later). Usually about 2 to 4 embryo transfer into the uterus during data transmission, and the remaining embryos, if the embryo using stored procedures are stored by freezing in the event of failure to be used next treatment cycle. Embryo transfer is done in the operating room but do not require anesthesia. Only patients were examined on the bed and then embryos with thin roots level through the hole for the mouth of the womb, the uterus is sent. This process is painless but sometimes mild pain feels .
After transfer and short breaks, guiding the patient to the hospital and a few hours after the clearance .
◄ effects ICSI:
Hayprastymvlyshn syndrome (overstimulation of the ovaries), rarely anesthesia, bleeding, infection, damage to the Rv BC, bowels and bladder during oocyte and twining
In case of problems following immediately contact your doctor or medical staff :
1 Spotting 2. 3. Shortness of breath, abdominal pain, fever over 38 ° C 4. 5. Blood in the urine
Tubal embryo transfer ZIFT
During practice ZIFT Eggs fertilized by laparoscopic surgery are transferred into the fallopian tubes. Then the fertilized egg to the uterus migrates and is replaced .
◄ advantage of practice ZIFT:
in practice ZIFT Jenin is the chance that the fallopian tube to the uterus itself over and replaced and the process was similar to normal pregnancy .
◄ disadvantages action ZIFT:
Action ZIFT Is an invasive procedure and need to do the surgery and anesthetic drugs used twice, once a day and once a day Tkhmkgyry
Embryo transfer tube chance to practice twining ZIFT In about 35 percent. The following odds ZIFT + ICSI Zyadtrmybashd .
◄ What to do ZIFT they are proper?
Women with ovulation problems who have at least one healthy fallopian tube . IUI Repeated unsuccessful cases where there is a cervical blockage and easily embryo transfer
The cervix is not possible .
◄ What to do ZIFT Not suitable?
1. Women who are damaged or blocked fallopian tubes .
2. In cases where there is a risk syndromes Hayprastyamashn .
3. Uterine infections (PID)
4. scar and adhesions in abdominal surgery
◄ steps ZIFT:
– Step ovulation :
Fertility drugs to get high egg and the formation of several fetuses and increase the chances of fertility prescribed. They’re usually on the second day of menstruation and after ultrasound and ensure the integrity of the uterus and Tkhmda they are given. Growth eggs teeth with ultrasound successive patient follow-up. Therefore, it is possible to reach the ideal situation several times at intervals of 2 to 3 days to be placed under ultrasound, the ultrasound follicle size of 18 to 20 mm, mates HCG The final oocyte maturation prescribed. Time injections HCG It is very important because approximately 34 to 36 hours after injection ovulation and therefore time should be determined according to the doctor to release eggs to be collected .
– The collection of eggs and sperm :
Be sure the patient is fasting on the day of oocyte. Semen from the patient’s wife prepared and delivered to the laboratory. After washing and preparation of laboratory samples to the laboratory it IVF Delivers. A mild anesthetic to the patient in the operating room during the process of oocyte discomfort. Oocytes under direct vision with Ultrasonic devices made by a very thin needle and collected into special tubes and laboratory IVF Delivered .
– In vitro fertilization fetus was submerged :
in the lab IVF Eggs are isolated from follicular fluid, washed and placed in a medium inside the container. Wife washed sperm lab which had already been delivered along with this egg is placed in the container, the container samples of sperm and eggs in incubator CO2 Placed at 37 ° C to spontaneously find each other fertilization. The next morning when the fertilized embryos into the incubator for 24 to 48 hours are 4 to 8-cell stage to reach. If the patient undergoing ZIFT The next morning the laboratory is oocyte fertilization on their own and call center makes sure. Whereas there is no prohibition embryologists and physiciansand gynecologists fertilized egg is present, the patient who is fasting with his wife. After the admission procedure, the patient was sent to the operating room under general anesthesia and during laparoscopic surgery, tubal embryo will be entered into a special catheter .
Embryo Donation
The most commonly cited reasons for using donated embryos, gentlemen azoospermia (absence of sperm) is. Other common causes, genetic disorders or specific chromosomal .
